We present transient simulations of the last glacial inception with the coupled climate–ice sheet model CLIMBER-X showing a rapid increase in Northern Hemisphere ice sheet area and a sea level drop by ~ 35 m, with the vegetation feedback playing a key role. Overall, our simulations confirm and refine previous results showing that climate-vegetation–cryosphere–carbon cycle feedbacks play a fundamental role in the transition from interglacial to glacial states.