The reactivity of local to regional hydrosystems to global changes remains understated in East African climate models. By reconstructing a chronicle of seasonal floods and droughts from a lacustrine sedimentary core, this paper highlights the impact of El Niño anomalies in the Awash River valley (Ethiopia). Studying regional hydrosystem feedbacks to global atmospheric anomalies is essential for better comprehending and mitigating the effects of global warming in extreme environments.